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Thalidomide-O-amido-PEG-C2-NH2 hydrochloride

CAS No. 2204226-02-6

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride ( —— )

Catalog No. M27020 CAS No. 2204226-02-6

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 46 Get Quote
10MG 67 Get Quote
25MG 110 Get Quote
50MG 160 Get Quote
100MG 241 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
  • Description
    Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Mitochondrial Metabolism
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2204226-02-6
  • Formula Weight
    454.9
  • Molecular Formula
    C19H23ClN4O7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.NCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang Y, et al. A new point mutation in the iron-sulfur subunit of succinate dehydrogenase confers resistance to boscalid in Sclerotinia sclerotiorum. Mol Plant Pathol. 2015 Sep;16(7):653-61.
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